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Figure 9 Endometrial carcinoma pathways in the combined target list

Figure 9 Endometrial carcinoma pathways in the combined target list

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Figure 9 Endometrial carcinoma pathways in the combined target list of hsa-miR-181a-5p based on both TarBase and miRTarBase 4.0.

Figure 2 Wnt signaling pathway in the target list of hsa-miR-181a-

Figure 4 pathway in the target list of based on TarBase

Figure 6 MAPK signaling pathway in the target list of hsa-miR-181a-

Figure 7 Notch signaling pathway in the target list of hsa-miR-181a-5p based on miRTarBase 4.0.

Figure 8 VEG F signaling pathway in the target list of hsa-miR-181a

Figure 5 Cancer pathways in the target list of hsa-miR-181a-5p

Figure 5 Cancer pathways in the target list of hsa-miR-181a-5p based on miRTarBase 4.0. | hsa-miR-181a and endometrial carcinoma | Pinterest

Figure 3 Cell cycle pathway in the target list of hsa-miR-181a-

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notch signaling pathway in the target list of hsa-mir-181a-5p based

Figure 7 Notch signaling pathway in the target list of hsa-miR-181a-5p based on miRTarBase 4.0. Notes: hsa-miR-181a-5p can regulate the function of the ...

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The expression level of miRNA in Normal and Endometrium Cancer. The five miRNA (hsa

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Figure 6 MAPK signaling pathway in the target list of hsa-miR-181a-5p based on miRTarBase 4.0. Notes: hsa-miR-181a-5p can regulate MAPK signaling pathways.

The position of miRNA targeted genes (red box) in endometrial carcinogenesis pathway (KEGG

Figure 1. Molecular and genomic heterogeneity of endometrial cancer

Targeting STAT3 proinflammatory pathway. Schematic representation of the major targetable events during STAT3 activation,

Therapeutic molecular targets for endometrial cancer. Type I endometrial cancer (EC) frequently exhibits

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Figure 12 Proposed mechanisms for how hsa-miR-181a regulates cancer genes and may

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FIGURE 2: Schematic of the components of the angiogenic pathway and antiangiogenic agents.56

The twelve miRNA might regulate Endometrial Cancer pathway (A). The miRNA also controlled

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Figure 10 The expression of ER and PR in type I EC . | hsa-miR-181a and endometrial carcinoma | Pinterest

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Pathway Enrichment Map of dyregulated protein complexes. Pathway Enrichment Map of dyregulated protein complexes.

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Figure 5 Cancer pathways in the target list of hsa-miR-181a-5p based on miRTarBase 4.0. | hsa-miR-181a and endometrial carcinoma | Pinterest

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(Continued )

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Figure 1

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Effect of vorinostat on the mTor and Ampk signaling pathway in endometrial cancer cells. Ishikawa

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Regulation of IGF-IR promoter activity by vorinostat in endometrial cancer cells. Ishikawa and

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Differential signaling domain enrichment of epigenetic versus genetic alterations within the chemokine signaling pathway. (

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Association of TFs, target mRNAs and significant KEGG pathways with hsa-miR-92a

Targeting the CSC/EMT signaling pathways in EC. Tumor cells that undergo EMT not

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Figure 4 p53 pathway in the target list of hsa-miR-181a-5p, based on TarBase 6.0. Notes: hsa-miR-181a-5p can regulate the p53 signaling pathway. p53 is ...

Potential miRNA-based therapies in EC. The use of antibodies against cell surface markers · Targeting immunosuppressive molecular pathways ...

Figure 3: Signaling through the NOTCH1 pathway induces migration and an EMT phenotype in SHARP1

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Functional epigenetic alterations preferentially target genes in the extra-cellular/transmembrane domains, with

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Effect of vorinostat on the cell cycle in endometrial cancer cells.

RTK (Receptor tyrosine kinases)/RAS/PI3K/AKT/mTOR signaling pathway

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Graphical Abstract

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(Continued )

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Flow chart showing the selection of endometrioid endometrial carcinoma cases from the Cancer Genome Atlas (

Functional epigenetic alterations exhibit lower interactome connectivity than their SCNA counterparts. Left panels: for

MiR-361 directly targets Twist and modulates its downstream genes.

Figure 3 Cell cycle pathway in the target list of hsa-miR-181a-5p, based on TarBase 6.0. Notes: hsa-miR-181a-5p can regulate a number of important proteins ...

Figure 3. Significant pathways of genes involved in the differential modules in the four types of ovarian cancer (endometrioid, serous, mucinous and clear ...

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Fig. 3

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Figure 8 VEGF signaling pathway in the target list of hsa-miR-181a-5p based on miRTarBase 4.0. Notes: hsa-miR-181a-5p can regulate the VEGF signaling ...

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Figure 3

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Figure 2. ASLNC04080 was upregulated in endometrial carcinoma tissues. (A) ASLNC04080 expression was increased in 92% endometrial carcinoma tissues (EC) ...

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Figure 6

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Graphical Abstract

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S1 Fig. Principal component analysis of microarray experiments in the three gynecological cancers and their normal controls.

Correlation between somatic mutations and transcripts in endometrial cancers.

let-7b and miR-361 are tumor suppressors potentially regulated by EZH2.

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Canonical Wnt-FZD signaling pathway gr1_lrg

Survival meta-analysis for six trials (1135 patients) comparing more intensive with less

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Figure 3. Figure 3. Inflammatory aspects of endometrial adenocarcinoma.

S1 Fig. KEGG Oxytocin Signaling Pathway.